Hotels/Motels go Results Found: 4 Button group with nested dropdown Drury Inn & Suites Drury Inn & Suites 2608 E. Malone Sikeston MO 63801 (573) 472-2299 Hampton Inn Hampton Inn 1240 Commerce Dr Sikeston MO 63801 (573) 621-4100 Best Western Hotel Best Western Hotel 120 S. Interstate Drive Sikeston MO 63801 (573) 481-9500 Holiday Inn Express & Suites Holiday Inn Express & Suites 115 Hospitality Dr. Sikeston MO 63801 (573) 475-9522